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Vitamin B12 deficiency can be caused by any of the following: Pernicious anaemia is a condition of the immune system

These changes are particularly relevant with aging, diabetes, chronic kidney disease, prolonged hyperglycemia, and disorders involving phosphate and mineral metabolism

[2] [1] With neurological involvement: Hydroxocobalamin 1mg intramuscularly on alternate days until no further improvement, then maintenance injections every 2 months

One case study evaluated: Day 1 : 1500mg Day 2 : 1000mg Days 3 : 750mg Day 4 and 5 : no treatment Days 6 and 7 : 750mg Day 8 and 9 : 500mg Day 10 : 750mg Ongoing treatment: 1000mg infusion every 4-6 weeks and 120mg NAD+ nasal every day The study found patients hand tremors decreased over treatment and visual hallucinations were absent on days two through seven of treatment

Beshyah, Amin Jayyousi, Ali Saif Al-Mamari, Ashraf Shaaban, Ebaa Al Ozairi, Jalal Nafach, Mahir Khalil Ibrahim Jallo, Said Khader, and Marc Evans contributed to the study conception and design